Mentor  Pharmaceutical Consulting


 
 
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  Publications :

  1. Ey, P. L., G. J. Russell-Jones and C. R. Jenkins. 1980 Isotypes of mouse IgG. I. Evidence for "non-complement-fixing" IgG1 antibodies and characterization of their capacity to interfere with IgG2 sensitisation of target red blood cells for lysis by complement. Molecular Immunol., 17 : 699-710.

  2. Russell-Jones, G. J., Ey, P. L. and Reynolds, B. L. 1980 The ability of IgA to inhibit the complement-mediated lysis of target red blood cells sensitised with IgG antibody. Immunol. 17 : 1173-1180

  3. Russell-Jones, G. J., Ey, P. L. and Reynolds, B. L. 1981 Inhibition of Cutaneous Anaphylaxis and Arthus Reactions in the mouse by antigen-specific IgA. Int. Arch. Allergy appl. Immunol., 66 : 316-325.

  4. Russell-Jones, G. J., Ey, P. L. and Reynolds, B. L. 1984 The ability of IgA to inhibit complement consumption by complement-fixing antigens and antigen-antibody complexes. Aust. J. Exp. Biol. Med. Sci., 62 : 1-10.

  5. Blake, M. S., Johnston, K. H., Russell-Jones, G. J. and Gotschlich, E.C. 1984 A rapid, sensitive method for detection of Alkaline-Phosphatase-Conjugated Anti-Antibody on Western blots. Anal. Biochem., 136 :175-179.

  6. Russell-Jones, G. J., Gotschlich, E. C. and Blake, M. S. 1984 A surface receptor specific for human IgA on Group B streptococci possessing the Ibc protein antigen. J. Exp. Med., 160 : 1467-1475.

  7. Russell-Jones, G. J. and Gotschlich, E. C. 1984 Identification of protein antigens of Group B streptococci, with special reference to the Ibc antigens. J. Exp. Med., 160 : 1476-1484.

  8. Russell-Jones, G. J. and Aizpurua, H. J. de. 1987 Mucosal Immunogens In: Recent Advances in Mucosal Immunology,. Ed. J. Mestecky, J. R. McGhee, J. Bienenstock and P. L. Ogra. (Plenum Publishing Co, New York and London) Adv. Exp. Med. Biol., 216B, 1791-1799.

  9. de Aizpurua, H. J. and G. J. Russell-Jones 1987 Oral vaccination: Identification of classes of proteins which provoke an immune response upon oral feeding. J. Exp. Med. 167 : 440-451http://www.jem.org/cgi/reprint/167/2/440

  10. Russell-Jones, G. J. and H. J. de Aizpurua. 1988 Vitamin B12 : A novel carrier for orally presented antigens. Proceed. Int. Symp. Control. Rel. Bioact. Mater. 15 : 142-143.

  11. Croft, S., Walsh, J., Lloyd, W., & Russell-Jones, G. J. 1991 Tra-T : a powerful carrier molecule for the stimulation of immune responses to protein and peptide antigens. J. Immunol. 146 : 793-798

  12. Bergmann, K.-C., Waldman, R. H., Bicak, M., & Russell-Jones, G.J. 1989 Adjuvant effect of B-subunit of E.coli heat labile toxin on secretory antibody response to oral influenza virus immunization in mice. Allergologie. 12 : 294.

  13. Croft, S. Russell-Jones, G. J., and Geczy, A. F. 1990 ISCAR : a highly immunogenic carrier which elicits strong immune responses to peptide and protein antigens. Vaccines 90, C24.

  14. Bergman, K.-C., Russell-Jones, G.J. and Waldman, R.H.. 1991 B Subunit of E. Coli heat-labile enterotoxin enhances secretory IgA antibody response to oral influenza virus immunization in mice. Schweizerische Medizinische Wochenschrift. 121 : Suppl 40/II, 28.

  15. Stewart, A., Valentine, J., Tsonis, C., Borchers, C., Russell-Jones, G., Headon, D., Worral, M., Clifton, G., McInerney, B., and Forage, R. 1992 Immunization using receombinant TraT-LHRH fusion proteins. Vaccines 92, 51-55 (Cold Spring Harbor Laboratory Press).

  16. Russell-Jones, G.J., Sullivan, J.S. and Geczy, A.F.. 1993 Peptide sequences with strong T-cell stimulatory activity in phylogenetically diverse species: implications for vaccine development. Vaccine 11: 1310-1315.

  17. Russell-Jones, G.J. 1993 Oral Vaccination with Lectins and Lectin-Like Molecules. In "Novel Delivery Systems for Oral Vaccine Development" Ed. Derek O'Hagan, CRC Press pp 296-299.

  18. Russell-Jones, G.J. 1995 Oral delivery of Therapeutic Proteins and peptides by the vitamin B12 uptake system. In "Peptide-based Drug Design: Controlling Transport and Metabolism." Ed. M. Taylor and G. Amidon, ACS Publications pp181-198.

  19. Russell-Jones, G.J. 1993 Oral delivery systems for proteins and peptides: The use of lectins for oral immunization and the use of the VB12-uptake system for the delivery of peptide and protein pharmaceuticals. Proceed. of "Business Opportunities in Peptide and Protein Delivery". Leiden, Netherlands

  20. Bell, S. J. D. Geczy, A. F., Russell-Jones, G. J., Croft, S., Cooper, D. A. and Penny, R. 1993 Augmentation of HIV-specific lymphoproliferation in HIV-infected individuals by TraT: a novel T cell immunopotentiating agent. AIDS : 807-812.

  21. Lazorov? L., Sjölander, A., Russell-Jones, G.J., Lindner, J. and Artursson, P. 1993. Intestinal tissue distribution and epithelial transport of the oral immunogen LTB, the B subunit of E. coli heat-labile enterotoxin. J. Drug Targeting 1, 331-40

  22. Russell-Jones, G.J. 1994 Oral delivery of Therapeutic Proteins and Peptides by the Vitamin B12 Uptake System. In "Pharmaceutical Manufacturing International" Ed P Barnacal.

  23. Lindner, J., Geczy, A. F. and Russell-Jones, G. J. 1994 Identification of the site of uptake of the E. coli Heat-Labile enterotoxin, LTB. Scand. J. Immunol. 40, 564-572.

  24. Habberfield, A., Jensen-Pippo, K., Ralph, L., Westwood, S. W. & Russell-Jones, G. J. 1996. Vitamin B12-mediated uptake of erythropoietin and granulocyte colony stimulating factor in vitro and in vivo. Int. J. Pharmacol., 145, 1-8

  25. Russell-Jones, G. J., Westwood, S. W. & Habberfield, A. 1995. Vitamin B12 mediated oral delivery systems for Granulocyte Colony Stimulating Factor and Erythropoietin. Bioconjugate Chemistry, 6, 459-465

  26. Russell-Jones, G. J., Westwood, S. W., Farnworth, P. G., Findlay, J. K. & Burger, H. G. 1995 Synthesis of LHRH antagonists suitable for oral administration via the Vitamin B12 uptake system. Bioconjugate Chemistry, 6, 34-42.

  27. Russell-Jones, G. J. 1996 The potential use of receptor-mediated endocytosis for oral drug delivery. In “Carrier mediated approaches for oral drug delivery?Advanced Drug Delivery Reviews, 20, 83-96. Eds. Øie, S., Szoka, F. C., and Swaan, P. W.

  28. Gordon, M. M., Russell-Jones, G. J., & Alpers, D. H. (1997) Expression of functional intrinsic factor using recombinant baculovirus. Methods in Enzymology, Vol. 281, 255-261.

  29. Russell-Jones, G. J. (1996) Utilisation of the Natural Mechanism for Vitamin B12 uptake for the oral delivery of therapeutics. Eur. J. Pharm. Biopharm. 42, 241-249.

  30. Habberfield, A., Jensen-Pippo, K., Ralph, L., Westwood, S. W. and Russell-Jones, G. J. 1996 Vitamin VB12-mediated uptake of recombinant therapeutic proteins from the gut. Int. J. Pharm., 145, 1-8.

  31. Russell-Jones, G. J. 1999 Carrier-mediated transport for oral drug delivery. Encyclopedia of Controlled Drug Delivery Ed. E. Mathiowitz

  32. Russell-Jones G. J., Arthur, L., and Walker, H. 1999 Vitamin B12-mediated transport of nanoparticles across Caco-2 cells Int J. Pharm., 179, 247-255.

  33. Russell-Jones, G. J. and Alpers, D. H. 1998 Vitamin B12 transporters. In “Membrane transporters as drug targets?Pharmaceutical Biotechnology Vol. 12 Ed. W. Sade? and G. Amidon. Plenum press. (Review).

  34. Russell-Jones, G. J. 1998 Use of Vitamin B12 conjugates to deliver protein drugs by the oral route. Critical Reviews in Therapuetic Drug Carrier Systems, 16, 557-558. (Review)

  35. Alpers, D. H., and Russell-Jones, G. J. 1999 Intrinsic factor and haptocorrin and their receptors. (In “Chemistry and Biochemistry of B12: Part II: Biochemistry of B12?Ed Ruma Banerjee, New York, Wiley)

  36. Russell-Jones G. J., Veitch, H. and Arthur, L. 1999 Lectin-mediated transport of nanoparticles across Caco-2 and OK cells (Int J. Pharm. 190, 165-174)

  37. Wen J, Kinnear MB, Richardson MA, Willetts NS, Russell-Jones GJ, Gordon MM, Alpers DH.Functional expression in Pichia pastoris of human and rat intrinsic factor. Biochim Biophys Acta. 2000 Jan 31;1490(1-2):43-53. PMID: 10786616 [PubMed - indexed for MEDLINE]

  38. McEwan, J. F., Veitch, H. S., and Russell-Jones, G. J. 1999 Synthesis and Biological Activity of ribose-5’carbamate derivatives of vitamin B12. Bioconj. Chem., 10, 1131-1136. :< http://dx.doi.org/10.1021/bc990086p> http://dx.doi.org/10.1021/bc990086p

  39. Russell-Jones, G. J. and Nelson-Smith, C. 1999 A literature review to examine the effect of tobacco additives on the bio-availability of nicotine. Contracted document to the NHMRC, Australia.

  40. Russell-Jones G. J. 1999 Use of bioconjugates for oral delivery of peptides, proteins and immunogens. In “Drug Delivery Science and Technology? STP Phama Sciences Janvier-Fevrier.

  41. Alsenz J, Russell-Jones GJ, Westwood S, Levet-Trafit B, de Smidt PC. 2000 Oral absorption of peptides through the cobalamin (vitamin B12) pathway in the rat intestine. Pharm Res. 2000 Jul;17(7):825-32.
    PMID: 10990201 [PubMed - indexed for MEDLINE]

  42. Russell-Jones, G. J. 2000 Oral vaccine delivery. J. Control. Rel., 65, 49-54.

  43. Russell-Jones G. J. 2000 Use of the vitamin B12 transport system to enhance the oral bioavailability of peptides and proteins. In “Drug Targeting in the Gastrointestinal Tract?Ed. Josef Tukker. Harwood Academic Publishers.

  44. Russell-Jones, G. J. 2001 The potential use of receptor-mediated endocytosis for oral drug delivery. In “Carrier mediated approaches for oral drug delivery?Advanced Drug Delivery Reviews, 46, 59-73. (Special commemorative edition. Eds. Øie, S., Szoka, F. C., and Swaan, P. W.).

  45. Russell-Jones, G. J. 2004 Use of targeting agents to increase uptake and localization of drugs to the intestinal epithelium. J. Drug Targ, 12, 113-23 (Review)

  46. Russell-Jones, G. J. McTavish, K, McEwan, J., Rice, J. R., Nowotnik, D. 2004 Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours. J. Inorg. Biochem., 98, 1625-1633.

  47. Chalasani, K. B., Russell-Jones, G. J., Yandrapu, S.K., Diwan, P. V., Jain, S. K. A novel vitamin B12-nanosphere conjugate carrier system for peroral delivery of insulin. J. Control. Rel. 2007, 117, 421-9

  48. Himes, R., Lee, S., McMenigall, K. and Russell-Jones, G. 2011 The influence of molecular adjuvants in the cutaneous response to antigen after topical vaccination. Vaccine, June 12, 29, 5393-8 PDF

  49. Russell-Jones, G. J. 2011 Intestinal receptor targeting for peptide delivery: Reasons for failure and new opportunities. Invited Review. Therapeutic Delivery 2, 12, 1575-1593. PDF

  50. Russell-Jones, G. J., McTavish, K. J. McEwan, J.F. 2011 Preliminary Studies on the Selective Accumulation of Vitamin-Targeted Polymers Within Tumours. J. Drug Targ. 19, 133-9 PDF ColourFigs

  51. Russell-Jones, G. J. and Himes, R. 2011 Water-in-oil Microemulsions for Effective Transdermal Delivery of Proteins. Expert Opinion in Drug Delivery. Invited review ?nbsp; 8, 537-546. PDF

  52. Russell-Jones, G. J. McTavish, K. J., McEwan, J. F., Thurmond, B. 2012 Increasing the tumoricidal activity of daunomycin-pHPMA conjugates using vitamin B12 as a targeting agent. J. Cancer Research Updates, 1, 203-211 PDF